Studies Related to 🔗 7ohBlack HoneyBee Gold
(74.1% 7ohm + 7.53% Pseudoindoxyl = 81.63% Total Alkaloids)
Our latest powdered botanical extract is meticulously standardized to 74.1% 7-hydroxymitragynine (7-OH) and 7.53% mitragynine pseudoindoxyl, delivering an ultra-potent yet balanced profile.
Recent scientific insights suggest that pushing alkaloid potency to extremes doesn’t always yield better outcomes—in fact, it may be counterproductive at the receptor level. For example, Hiranita et al. (2020) found that very high doses of 7-OH increased brain reward thresholds in rats, suggesting diminishing or aversive effects:
🔗 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542979
In line with these findings, we’ve chosen to keep our formulation under 80% total actives to support a more stable, nuanced receptor interaction. This isn’t just theory—our lab data and customer feedback consistently point to sub-80% formulations offering a smoother, more well-rounded experience (again, no medical claims—just observation and transparency).
Science-Backed Formulation
What sets this extract apart is its 7.53% mitragynine pseudoindoxyl content. According to Kruegel et al. (2016) in the Journal of Medicinal Chemistry, mitragynine pseudoindoxyl acts as a potent μ-opioid receptor agonist and a δ-opioid receptor antagonist, without recruiting β-arrestin-2—a signaling pathway often linked to unwanted receptor effects like tolerance:
🔗 https://pubs.acs.org/doi/10.1021/acs.jmedchem.6b00748
We highlight these findings to help educate—not to hype. Every batch is lab-verified for alkaloid content, and our reports are available for full transparency. Our mission is to stay on the pulse of research and deliver products that reflect what actually works best in practice, not just on paper.
Disclaimer: This product is sold strictly for botanical research and education. No medical or health claims are made. Always use responsibly and in accordance with applicable laws and guidelines.
7ohBlack Honeybee Gold Powder is a uniquely formulated botanical extract that packs an alkaloid punch. It is crafted by 7ohBlack with an educational and transparent approach in mind. In this article, we’ll break down what’s inside this product, explain the science in plain language, and discuss why those components matter – all while staying FDA-compliant (no medical claims here, just the facts and research!).
We’ll explore the two standout alkaloids in 7ohBlack Honeybee Gold Powder: 7-hydroxymitragynine and mitragynine pseudoindoxyl. These tongue-twister names come from the kratom plant (Mitragyna speciosa) and are known for their interesting effects in scientific studies. By the end, you’ll understand what makes this extract special, why more isn’t always better with 7-hydroxymitragynine, and how mitragynine pseudoindoxyl might offer powerful effects with fewer typical side signals. Let’s dive in.